Introduction
Imagine being able to correct an error written in the DNA code of a living cell, like correcting a spelling mistake in a book that contains instructions for life. This is what scientists can now do thanks to CRISPR-Cas9, a revolutionary genetic editing tool.
CRISPR has been described as a “molecular pair of scissors” (Doudna & Charpentier, 2014). It allows scientists to cut DNA at precise locations and modify it, removing defective genes or inserting healthy ones. This technology is already being studied for potential use in correcting genetic diseases, improving crops, and even fighting viruses.
This teaching unit introduces students to the basics of DNA, genes and CRISPR-Cas9, using interactive and accessible explanations. Following the Explore - Execute - Improve methodology, students will first discover the essential concepts, then experiment with the process in a virtual augmented reality laboratory, and finally reflect on the ethical and social impact of this new biotechnology.